Bench To Bedside

Bench to Bedside Outline A. What is judicature to bedside look for? * Described as test and error process where physician researchers find brand-new research in the laboratory and then do clinical trial runs on patients * Most of these patients be not gentlemans initially; researchers unremarkably tests on animals first before injecting the dose into human patients B. What argon some types of bench to bedside research? * Basic research- they contemplate jail cell structure of cells and try to determine whether they argon cancer cells or not. If they find some strange they displace it to * Preclinical- is the actual work that is through in the lab. There are two types of preclinical research called in vitro and in vivo. * In vitro means in glass; tests using cell lines and/or cell cultures contained in petri dishes and test tubes * In vivo means try let out without glass; testing on animals and collect information about the a ctivity of the drug ( cognise as pharmocodynamic testing), as well as absorption, distri thation, excretion known as (pharmacokinetic testing) and toxicity. C. What are the trials of bench to bedside research? * bod 1- judge the drugs and do research. Find out what dose of the drug is uninjured and how it should be given. * Phase 2- the trial and error part; appreciate the drug and take denary Is the drug effective? Does it fill further testing? conciliate the dose if these questions have been answered. * Phase 3- Tie the research together. side at predicted results and final results. rate the efficiency toward the standard of care. accordingly confirm or deny the dose. D. What are some examples of bench to bedside research being done? * One of the first examples that was utilize for bench to bedside research was Anti-angiogensis * Folkman who make his idea in 1971, but it wasnt until 2002 that Avastin, the VEGF inhibitior was appr oved for treating colon cancer * UGA re! searchers actually appoint a new treatment for...If you deficiency to get a full essay, order it on our website: BestEssayCheap.com

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